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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2822dea8ed7915e2f27947324923d801900344ea86b601a725e0e2981be32133' 
  AND token = 'c5KPOdL8LmBxqMR4hRr8RXjhDm8cyHOXWUrjtWhCkLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}