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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2adb1ffdfd6afeb31d039f9a7b3cedf014275b02dd6b96ac752c17128ee231' 
  AND token = '4yhaF+ucvPkA/1DjwdzIyZF1mz4qhn32h4PpzniOVk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}