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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc74eb869e5b2de6ee1d6ff9c9f091006e7877668c38e82815e2b13ea2ea696' 
  AND token = 'FPkyhgi3Q2pWphGyNq//PF89CxT2u5Tb3KqWPgq9X7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}