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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e05475390ecbb42a6fa3cbabbced2364034f1cd55a7b69e5e2c04110d5a8f8' 
  AND token = 'DIM5FhVFv6pQIQjXpGVuBiB01vS38cwiUdVy3u1OLoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}