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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49ac6818cb7ba4d9350c72d0cb36861b2b18d2eb194738019ca51bb78b91ce6' 
  AND token = '5tbHPjOj4hKYsDN3G7AkXaHjj6Dz+IIXHF9DuuOzx8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}