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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fbbbcf543cb4bf75b2834052fcc835ecd2eb9c246f3e4c3d5e0fecb202e187' 
  AND token = 'EOzuLZn4j4ssCdl2UHK/fdrhrEyO1bAUD4svAH1a8rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}