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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a48a26dfb1db3eb125aa981f755b38e7056d819abe672d1f1550230b758fd4e' 
  AND token = 'JjzbHQ2MTjrvtjgA2wB+6/GWXkmbfQ/dfrJ4R2ybzXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}