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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b55f22c829aa28b2e3c6cc3c38323d29475c72caf993d36582add5b12350f15' 
  AND token = 'Stob4qm5Z6Vx0+CZoc11LOW1GQjlIEzkdkzqy4cRaBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}