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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e3860d7a9bb0a145e98353d0361e552b8fb1aaabc163a0dbbbca256c5596359' 
  AND token = 'lxPa3b9bpjswEdShUQ8aflSY4P9T/iRcyuMMp+MsORI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}