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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a21a698d30a895785d760c4f1ccf02e003d1d13fb99f8cd1ab77736d39275e' 
  AND token = 'WWuiaJJjIB8t4CfZp82DV1jM5UMFsUMUrqrEyBwnVD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}