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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce452d1b5510169aacbb284d40b8ac8c39168d906138e1cc0485bee6ae2d1bc8' 
  AND token = 'B0nzPJnV4e3UP94g8iArHmHgIEPvg21nsDCpmjBokFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}