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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3d4bd4961987bba6e94b9b57e6db1c609f406f3a702963d57818171f77e84c' 
  AND token = 'JirsnisK9GNVibH1OO7beCFnVd2r9FDUuuo5sGd5yi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}