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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68644f9c7057bce777657b499c4e666cfa06a78a8b183290942ba4ca666a8843' 
  AND token = '/rsquBzNQFvKdI9TSmoehC0b32eSmqCO7bBDgNZHBTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}