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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db3cf9357cf2074dee6661cdbd841c1daef0dd52e1be22889a841995de4e856' 
  AND token = 'VhdQpraPNBEuPBmV3M6gqmsXGCnS2X3N1+Yi4dkzIH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}