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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2f88c4b75c5a2462c2a61e5c5dd68e2d079a7345bc5efd6ac883cde8c0c57d4' 
  AND token = '2V7s63HAMEjxc3pbf+bG5DFu3NZ6tCjQZqxsHs3j3Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}