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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d51e7ebe9a39b72a4024c78136faa18899a1636edb486c249f7ca86245605a9' 
  AND token = 'rOemCm4Ozsaf50XStJ1tREKe07F4jWSeATiDZ6wDX5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}