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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c5a6bdc23b79d1c2a7ab9740c2e2d76d4d970a85ea2843d48995b6297ea5ee' 
  AND token = 'uUxpb/I4r5exWyhtNCSgCPddpNqarNAu22pw3bdmD6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}