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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec58ac8c5653bdce7606d1ad7d345b2a2109a5b761002fa5fd83fb4c759260b1' 
  AND token = 'AdziS8GTV7SLgyd05uKKGyRwjn2itWLxX0vNBI4qwps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}