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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d22f99dc765fba898ada0ce452edd17d7e2f66e56e087d2222fee8cf3098be' 
  AND token = 'aqb05fq0U5vKRE9PEDrf8tXIzzmtK5n1Su7E8HReNhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}