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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9fb8169b1f1204788d2265dbe7a5fb55a0efb25edbd845d0d7be38b6c268c89' 
  AND token = 't6X5v3m8bXNugQsWdiwb64Q+9eOUQnAS7zUG4k5dNsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}