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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4582e6822dce11a2bcbd9d321264ce8d29b4c07557d74c7cfbc3e79ff944b72a' 
  AND token = 'fM7ZFp0ohx8hnionX3/8ohcPuSnxUL96IEXoYPm0Im8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}