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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6def2b0ca09fcbd3c925063d5890716ed833b4d926f320be0dd9831decf794a2' 
  AND token = 'Rdxr+0PpwKIs3FOrXd/gUBbuoBgrwjuEgJ+7eRbCeb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}