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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7d83d53794032b2d909c870cee1e48c8ae4e405b538e9f6052daa5f19eec30' 
  AND token = 'NdnBLJ5lMs2v+sk821TEgEa39nNaXNS87K5FqX2fLEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}