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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d10cdbfe1ebb348ec53a5dcc6dfc58f867465f4813667e58d47522d2655bedd' 
  AND token = '6R58TkMpbSSBBo6Cr4hzRMHpGu0jOR3GRIG0zXBuaek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}