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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de44cb6a25d5c51955f0587cd97354139b90946e527876c6d76a6a5326d79ef' 
  AND token = 'S+8bMoVFvLJDRPfHJGAU3oEt9HIKWZ4cduG5OK2LEUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}