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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1fc2d74dc9d16ccb0ef0c0d854ff531a9b540913f005a4c5b69c8b7b329f63b' 
  AND token = 'RP5v8KkghGtEgO02MkOtI7yViENIPyDvwtdxMzgvWQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}