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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c725124def9c74ea186d693ae02a800317065b6587c585e29bec9fb340fe1df' 
  AND token = 'a+acTZB1kde3aRilJuuhnOonLcUHtO99Y/v9C/rKEJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}