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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c5a8971e25a8071894ab320d448b6974e145e0b24624617da279424b81bfaa' 
  AND token = 'yEsUU+FRcmQxjrts1U++C6wQYibkq8btadsnFpaF/4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}