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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acc3a92fc3d1158a94a79806fe23f6c5b0f90d1e10d1bcb4af1bc31f5ec31ad8' 
  AND token = 'xm0B+DTErhYqFEXMEUtEwRJTXcAxr/5qt3u4Wcl/z+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}