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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3dcfed647e0a052b95560c2be3218fa786dceed9aacf5bf7825fbecf3c4ec70' 
  AND token = 'jf8IG64rmbwnPKe1XMcvKDdjIKfyyDfqQW7z0fVJ/j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}