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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3766962690aa347fe40f792160f4dcd2ffdac6bcbe5a22a9289462a9e0a1d71' 
  AND token = 'f/AEetGG2t5vyWnpQSjxLYSrmfASsP2YllRUodWNyhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}