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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43db4737afc91f875e402c06ef66cd9838dc6e9588e51d771224f3b8315fc76' 
  AND token = 'ytb1t0z3pkxJl1MyO/daOo+/hzddtXf6fSmiYdyhP8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}