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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743c8426edcea5eb49ae1613184e9f651bf1574501e896e9c4438812bdc3daf3' 
  AND token = '+1yA4J9a9ogfXqymHASizgLUbNfKSFlsdhwgiUQ5hIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}