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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dff9a0665c7be5da46f66b1fc23a69deb5a3c7bb0cf4a813f46aa3fdec43e16' 
  AND token = 'avNjwpbF4YE8ybs1bM1t5aVeR8eTwVN60t1Jdzt/Mp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}