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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cdf16c39fcc4bc9043ded18a81727e4a28c63860e9fdace1b34cde523ad0aa0' 
  AND token = 'w56AbRU53Fw+WNKA7LpQuT4Wxb7wUyQY7LCz3naKb4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}