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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef620936264a2c592cc548f2a200b01c3d4d36738894663ce4d48d3b5b731e55' 
  AND token = 'EO3TGMj8Nc6UZtpz7MNsMA4luxwaI1jDycmhtr3zeG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}