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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec7c2f4032bc1341ccc8e5fb8d41faf31bcc244839b2a05ed44c3cf6c74a595' 
  AND token = 'Zg2vKhDhL6dfHIoocTEr2d4iQgXJhapkHcZEOZc8x08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}