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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c1cd16e59f9bc02c2d067c3cf6df3c9421523394561016605b6ce04a87289b2' 
  AND token = '5rGfw9br1vFiRWxiffgFOYo0qdgghe9cjL7+PX8MG88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}