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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e1768f109ec1b0b626ada1c2d35d6251c8141fa8a4f0bde05e1f55462e850e' 
  AND token = 'tAulA11TSwqNukHkZAtmgg3J8+VbZsThJKVVt946p8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}