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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073d7eab572518013d67c35ceb0510eb0c8e4b97a8a4d52abffe54b288789a71' 
  AND token = 'JDo6GHVjSsPdH1tTg9I5GDebyGPf1nSGEDcJhapBf/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}