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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a91cf08fa450876c6a7f1ddfc83e8e6049cdcb8755955113b1cda93c06e557' 
  AND token = '/CwOA9ScxB67Q3SxDzCDItQ5+VOwukgKsdNDvdnv+ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}