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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '905814c49faea3d139b624308d4ae234ff29e7c5becd393d392a8c30af8b8c8c' 
  AND token = 'T3eRo1nYlNCu1YNq6RZRrPjGdmWM/Ktnxirh4xHzyGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}