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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2aac500f2bb258ae9e85b160ea340bf549bb73bd9a7d28d4bbbbc65f5b8964' 
  AND token = 'jF69hcjW32sy1j4LO+UGHSn8Xf/zRYIGGi2zyfoeTEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}