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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b0dc8e1ccc567036770c7808994da1fdbab2a45d4a1f7a8611f3845e44ee15' 
  AND token = 'ML3p6ILT38bUl96d7Q+YlGKHkEyXjeU6upUpvB0hsPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}