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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '102ba54391c324d99cf17cd508dfe427cf87af056150cce5a2da64d177652c36' 
  AND token = 'JdiI8ypZcCr2lrq2v83mG45Ga767VB3UwY5cCdR1aLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}