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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ae79c0f22a13881e23500f66fb8b5d2040b7018a5650e2ea6689e0017c1972' 
  AND token = 'oyeLQ07g17A7FCUTdpnHqO9V4aMDIb6xJP6ZstZG1k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}