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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64e622de47714e378b8d48aa07609e90983974a252c218f566da1d246b78555' 
  AND token = 'ZPCfXhzN/5D2I96u4yrlUvrLlQZb7E0Fz8XC2H9CMpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}