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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f5aa27f6df626c7431f2bb12d696493c0751fc4acb5c86f23fa762a3a77568c' 
  AND token = 'zppDkj2+8DzAaLXFbmIuiW7kW4gTlSyOTIKnx4mc6R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}