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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a80d4e79e5407f83574675775d7cb7aa0254e1b47a6bb60d5028bfe2d44a374' 
  AND token = 'mU7yDhQircgcVWlY+bDm3decZwvybPkPBfL8Bf/0R24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}