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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbbc4eb8085cf046f2e13f20fd080511498dbfa4f2e6d5434b487c2e26b3ad5' 
  AND token = 'ExiFmvaOBHVoy1RrG+xPQIdOc3gxvKgixVPMb8YdFE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}